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Key Features
Author Information
1 Voltage-Gated Sodium Channels and Electrical Excitability of the Heart
2 Voltage-Gated Calcium Channels
3 Voltage-Regulated Potassium Channels
4 Molecular Regulation of Cardiac Inward Rectifier Potassium Channel
5 Mammalian Calcium Pumps in Health and Disease
6 Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function
7 Organellar Ion Channels and Transporters
8 Gap Junctional Connexin 43: Novel Insights from the New Millennium and their Clinical Implications
9 Computational modeling and simulation for human cardiac electrophysiology: From induced pluripotent stem-cell derived cardiomyocytes to adult cardiomyocytes
10 Regulation of Cardiac Calcium Channels
11 Molecular Genetics of ATP-Sensitive Potassium Channels in Cardiovascular Diseases
12 Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity
13 Functional characterization of ion channel gene variants in sudden unexplained natural death
14 Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance
15 Connexins and Pannexins in Cardiovascular Disease
16 Excitation-Contraction Coupling
17 Ion Channel Trafficking in the Heart
17 Ion Channel Trafficking in the Heart
18 Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5
19 Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels
20 Macromolecular Complexes and Cardiac Potassium Channels
21 Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias
22 The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion and Cell Excitability
23 Function and Dysfunction of Ion Channel Membrane Trafficking and Post Translational Modification
24 Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling
25 Coupled Oscillators and Sinoatrial Pacemaker Activity
25 Coupled Oscillators and Sinoatrial Pacemaker Activity
26 Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants
27 Cell-to-Cell Communication and Impulse Propagation
28 Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation
29 Cell Biology of the Specialized Cardiac Conduction System
30 Computational Predictions of Drug-Induced Arrhythmias
31 Global Optimization Approaches to Generate Dynamically Robust Electrophysiological Models
32 Calcium Signaling in Cardiomyocyte Models with Realistic Geometries
33 Theory of Rotors and Arrhythmias
34 Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associated with Arrhythmic Risk Markers
35 Computational Approaches for Accurate Rotor localization in the Human Atria
36 Modeling the Aging Heart
37 Electromechanical Vortex Filaments During Cardiac Fibrillation
38 Innervation of the Sinoatrial Node
39 Autonomic and Oxidant Regulation of Cardiac Sodium Currents: Mechanisms and Consequences
40 Neural Activity and Atrial Tachyarrhythmias
41 Sympathetic Modulation of Cardiac Electrophysiology
42 Role of the Autonomic Nervous System in Atrial Fibrillation
43 Rotational and Focal Sources of Atrial Fibrillation: Scientific Rationale and Comparative Clinical Mapping
44 Nonivasive Frequency-Phase Mapping of Atrial Fibrillation
45 Mechanistic approaches for persistent AF ablation
46 Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation
47 Genetics of Atrial Fibrillation
48 Mechanisms in Genetic Sodium Channel Diseases
49 Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes
50 Inheritable Potassium Channel Diseases
51 Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation
52 Dominant Frequency as a Tool for Personalized Monitoring of Atrial fibrillation Progression and Upstream Therapy
53 Pharmacogenomics of Cardiac Arrhythmias
54 Screening Drugs for Myocardial Disease in Vivo with Zebrafish
55 Gene Therapy for Atrial Fibrillation
56 Cardiac Remodeling and Regeneration
57 High-Throughput Optical Mapping of 2-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing
58 Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors
59 The challenges of human iPSC-CM technology: Increasingly complex approaches improve cell maturation and relevance to modelling human cardiac disease
60 Assessment of the Patient With a Cardiac Arrhythmia
61 Differential Diagnosis of Narrow and Wide Complex Tachycardias
62 Electrocardiographic Monitoring: Short, Long-Term Recording
63 Personal Cardiac Monitoring
64 Computed Tomography for Electrophysiology
65 Magnetic Resonance Imaging for Electrophysiology
66 Intracardiac Echocardiography for Electrophysiology
67 Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk
68 Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Arrhythmias
69 Genetic Testing
70 Supraventricular Tachycardias: Diagnostic Maneuvers in the Electrophysiology Laboratory
71 Atrial Tachycardia
72 Atrioventricular Nodal Reentrant Tachycardia
73 Junctional Tachycardia
74 Preexcitation, Atrioventricular Reentry, Variants
75 Atrial Fibrillation: Mechanisms, Clinical Features, and Management
76 Ablation for Atrial Fibrillation
77 Left Atrial Appendage Management
78 Typical and Atypical Atrial Flutter: Mapping and Ablation
79 Sudden Cardiac Death in Adults
80 Premature Ventricular Complexes
81 Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management
82 PVC Ablation with Anatomic Guidance: Papillary Muscle, Moderator Band and Valve Annulus Sites
83 Fascicular Ventricular Arrhythmias
84 Bundle Branch Reentry Tachycardia
85 Ischemic Heart Disease
86 Ablation of Post-Myocardial Infarction Ventricular Tachycardia
87 Ventricular Tachycardia in Patients with Dilated Cardiomyopathy
88 Lamin A/C, Noncompaction and Other Genetic Cardiomyopathies with Ventricular Arrhythmias
89 Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators
90 Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
91 Catecholaminergic Polymorphic Ventricular Tachycardia
92 Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy
93 Ventricular Arrhythmias in Takotsubo Cardiomyopathy
94 Mitral Valve Prolapse, ventricular arrhythmias and Sudden Death
95 Brugada Syndrome
96 Long and Short QT Syndromes
97 Andersen-Tawil Syndrome
98 Timothy Syndrome
99 J-Wave Syndromes
100 Idiopathic and Short-Coupled Ventricular Fibrillation
101 Mapping and Ablation of Ventricular Fibrillation
102 Drug-Induced Ventricular Arrhythmias
103 Syncope
104 Sinus Node Abnormalities
105 Postural Orthostatic Tachycardia Syndrome
106 Atrioventricular Block
107 Sex Differences in Arrhythmias
108 Sudden Cardiac Deaths in Athletes, Including Commotio Cordis
109 Cardiac Sarcoidosis
110 Sleep-Disordered Breathing and Arrhythmias
111 Ventricular Assist Devices and Cardiac Transplant Recipients
112 Arrhythmia in Neurologic Disease
113 Cancer Therapy Related Arrhythmias
114 Arrhythmias in the Pediatric Population
115 Supraventricular Tachycardias in Congenital Heart Disease
116 Ventricular Arrhythmias in Congenital Heart Disease
117 Antiarrhythmic Drugs
118 Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death
119 Oral Anticoagulants
120 Implantable Pacemakers
121 Implantable Cardioverter Defibrillators: Technical Aspects
122 Transvenous Implantable Cardioverter Defibrillator: Clinical Aspects
123 Subcutaneous Implantable Cardioverter Defibrillators
124 Wearable Defibrillators
125 Cardiac Resynchronization
126 Management of Implanted Device Infections
127 Electrogram Recording and Signal Processing
128 Electroanatomic Mapping for Arrhythmias
129 Mapping Scar-Related Arrhythmias
130 Radiofrequency Ablation
131 Cryoablation and Other Radiofrequency Alternatives
132 Transvascular Ethanol Ablation
133 Cardiac Radioablation
134 Epicardial Approach in Electrophysiology
135 Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias
136 Surgery for Ventricular Arrhythmias
137 Neuromodulation for the Treatment of Arrhythmias
Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition
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Descripcion del producto
| ISBN Number | 9780323757454 |
| Main Author | Edited by Jose Jalife, MD, PhD and William Gregory Stevenson, MD |
| Copyright Year | 2023 |
| Edition Number | 8 |
| Format | Book |
| Trim | 276 x 216 (8 1/2 x 10 7/8) |
| Imprint | Elsevier |
| Page Count | 1696 |
| Publication Date | 15 Dec 2021 |
| Stock Status | NOT YET PUBLISHED Expected Release Date: 2021-12-15 |
Book Description
Fully updated from cover to cover,Zipes andJalife?sCardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides thecomprehensive, multidisciplinary coverageyou need?from new knowledge in basic science to the latest clinical advances in the field. Drs. JoséJalifeand William Gregory Stevenson lead a team of global experts who providecutting-edge content and step-by-step instructionsfor all aspects of cardiac electrophysiology.
Key Features
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Packs each chapter with the latest information necessary for optimal basic research as well as patient care.
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Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices.
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Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation.
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Includes 47 new chapters covering both basic science and clinical topics.
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Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management.
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Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online.
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Recipient of a 2018 Highly Commended award from the British Medical Association.
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author Information
Edited by Jose Jalife, MD, PhD, Distinguished Senior Investigator, Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain. Emeritus Professor of Internal Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan. and William Gregory Stevenson, MD, Director, Cardiac Arrhythmia Program, Cardiovascular Division, Brigham and Women's Hospital; Professor of Medicine Harvard Medical School, Boston, MA
Book Contents
1 Voltage-Gated Sodium Channels and Electrical Excitability of the Heart
2 Voltage-Gated Calcium Channels
3 Voltage-Regulated Potassium Channels
4 Molecular Regulation of Cardiac Inward Rectifier Potassium Channel
5 Mammalian Calcium Pumps in Health and Disease
6 Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function
7 Organellar Ion Channels and Transporters
8 Gap Junctional Connexin 43: Novel Insights from the New Millennium and their Clinical Implications
9 Computational modeling and simulation for human cardiac electrophysiology: From induced pluripotent stem-cell derived cardiomyocytes to adult cardiomyocytes
10 Regulation of Cardiac Calcium Channels
11 Molecular Genetics of ATP-Sensitive Potassium Channels in Cardiovascular Diseases
12 Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity
13 Functional characterization of ion channel gene variants in sudden unexplained natural death
14 Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance
15 Connexins and Pannexins in Cardiovascular Disease
16 Excitation-Contraction Coupling
17 Ion Channel Trafficking in the Heart
17 Ion Channel Trafficking in the Heart
18 Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5
19 Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels
20 Macromolecular Complexes and Cardiac Potassium Channels
21 Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias
22 The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion and Cell Excitability
23 Function and Dysfunction of Ion Channel Membrane Trafficking and Post Translational Modification
24 Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling
25 Coupled Oscillators and Sinoatrial Pacemaker Activity
25 Coupled Oscillators and Sinoatrial Pacemaker Activity
26 Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants
27 Cell-to-Cell Communication and Impulse Propagation
28 Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation
29 Cell Biology of the Specialized Cardiac Conduction System
30 Computational Predictions of Drug-Induced Arrhythmias
31 Global Optimization Approaches to Generate Dynamically Robust Electrophysiological Models
32 Calcium Signaling in Cardiomyocyte Models with Realistic Geometries
33 Theory of Rotors and Arrhythmias
34 Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associated with Arrhythmic Risk Markers
35 Computational Approaches for Accurate Rotor localization in the Human Atria
36 Modeling the Aging Heart
37 Electromechanical Vortex Filaments During Cardiac Fibrillation
38 Innervation of the Sinoatrial Node
39 Autonomic and Oxidant Regulation of Cardiac Sodium Currents: Mechanisms and Consequences
40 Neural Activity and Atrial Tachyarrhythmias
41 Sympathetic Modulation of Cardiac Electrophysiology
42 Role of the Autonomic Nervous System in Atrial Fibrillation
43 Rotational and Focal Sources of Atrial Fibrillation: Scientific Rationale and Comparative Clinical Mapping
44 Nonivasive Frequency-Phase Mapping of Atrial Fibrillation
45 Mechanistic approaches for persistent AF ablation
46 Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation
47 Genetics of Atrial Fibrillation
48 Mechanisms in Genetic Sodium Channel Diseases
49 Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes
50 Inheritable Potassium Channel Diseases
51 Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation
52 Dominant Frequency as a Tool for Personalized Monitoring of Atrial fibrillation Progression and Upstream Therapy
53 Pharmacogenomics of Cardiac Arrhythmias
54 Screening Drugs for Myocardial Disease in Vivo with Zebrafish
55 Gene Therapy for Atrial Fibrillation
56 Cardiac Remodeling and Regeneration
57 High-Throughput Optical Mapping of 2-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing
58 Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors
59 The challenges of human iPSC-CM technology: Increasingly complex approaches improve cell maturation and relevance to modelling human cardiac disease
60 Assessment of the Patient With a Cardiac Arrhythmia
61 Differential Diagnosis of Narrow and Wide Complex Tachycardias
62 Electrocardiographic Monitoring: Short, Long-Term Recording
63 Personal Cardiac Monitoring
64 Computed Tomography for Electrophysiology
65 Magnetic Resonance Imaging for Electrophysiology
66 Intracardiac Echocardiography for Electrophysiology
67 Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk
68 Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Arrhythmias
69 Genetic Testing
70 Supraventricular Tachycardias: Diagnostic Maneuvers in the Electrophysiology Laboratory
71 Atrial Tachycardia
72 Atrioventricular Nodal Reentrant Tachycardia
73 Junctional Tachycardia
74 Preexcitation, Atrioventricular Reentry, Variants
75 Atrial Fibrillation: Mechanisms, Clinical Features, and Management
76 Ablation for Atrial Fibrillation
77 Left Atrial Appendage Management
78 Typical and Atypical Atrial Flutter: Mapping and Ablation
79 Sudden Cardiac Death in Adults
80 Premature Ventricular Complexes
81 Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management
82 PVC Ablation with Anatomic Guidance: Papillary Muscle, Moderator Band and Valve Annulus Sites
83 Fascicular Ventricular Arrhythmias
84 Bundle Branch Reentry Tachycardia
85 Ischemic Heart Disease
86 Ablation of Post-Myocardial Infarction Ventricular Tachycardia
87 Ventricular Tachycardia in Patients with Dilated Cardiomyopathy
88 Lamin A/C, Noncompaction and Other Genetic Cardiomyopathies with Ventricular Arrhythmias
89 Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators
90 Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
91 Catecholaminergic Polymorphic Ventricular Tachycardia
92 Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy
93 Ventricular Arrhythmias in Takotsubo Cardiomyopathy
94 Mitral Valve Prolapse, ventricular arrhythmias and Sudden Death
95 Brugada Syndrome
96 Long and Short QT Syndromes
97 Andersen-Tawil Syndrome
98 Timothy Syndrome
99 J-Wave Syndromes
100 Idiopathic and Short-Coupled Ventricular Fibrillation
101 Mapping and Ablation of Ventricular Fibrillation
102 Drug-Induced Ventricular Arrhythmias
103 Syncope
104 Sinus Node Abnormalities
105 Postural Orthostatic Tachycardia Syndrome
106 Atrioventricular Block
107 Sex Differences in Arrhythmias
108 Sudden Cardiac Deaths in Athletes, Including Commotio Cordis
109 Cardiac Sarcoidosis
110 Sleep-Disordered Breathing and Arrhythmias
111 Ventricular Assist Devices and Cardiac Transplant Recipients
112 Arrhythmia in Neurologic Disease
113 Cancer Therapy Related Arrhythmias
114 Arrhythmias in the Pediatric Population
115 Supraventricular Tachycardias in Congenital Heart Disease
116 Ventricular Arrhythmias in Congenital Heart Disease
117 Antiarrhythmic Drugs
118 Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death
119 Oral Anticoagulants
120 Implantable Pacemakers
121 Implantable Cardioverter Defibrillators: Technical Aspects
122 Transvenous Implantable Cardioverter Defibrillator: Clinical Aspects
123 Subcutaneous Implantable Cardioverter Defibrillators
124 Wearable Defibrillators
125 Cardiac Resynchronization
126 Management of Implanted Device Infections
127 Electrogram Recording and Signal Processing
128 Electroanatomic Mapping for Arrhythmias
129 Mapping Scar-Related Arrhythmias
130 Radiofrequency Ablation
131 Cryoablation and Other Radiofrequency Alternatives
132 Transvascular Ethanol Ablation
133 Cardiac Radioablation
134 Epicardial Approach in Electrophysiology
135 Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias
136 Surgery for Ventricular Arrhythmias
137 Neuromodulation for the Treatment of Arrhythmias
